Journal Article

Doing the right things and doing them the right way: association between hospital guideline adherence, dosing safety, and outcomes among patients with acute coronary syndrome.

Mehta RH; Chen AY; Alexander KP; Ohman EM; Roe MT; Peterson ED.

Guidelines for the care of patients with acute coronary syndromes recommend aggressive therapy with certain medications, such as antiplatelet therapies that carry a risk of bleeding complications. This cohort study found only a weak relationship between quality (measured as adherence to guideline-recommended therapy) and safety (measured as major bleeding rates) at the individual hospital level. Hospitals that maximized both quality and safety had the best patient outcomes.