This article, co-authored by the immediate past presidents of the American Association of Critical Care Nursing and the American College of Chest Physicians, calls for improving patient safety in the intensive care unit (ICU) by redesigning the ICU work environment to achieve collaborative, patient-centered care. The authors cite the recommendations of the seminal Institute of Medicine reports on medical errors and health care quality as drivers of their recommendations to carry out multidisciplinary education and patient care, encourage patient participation in safety measures, and evaluate providers on their teamwork skills. An accompanying editorial (available via the link below) lauds these initiatives but cautions that significant cultural barriers will need to be overcome before true patient-centered care can be achieved.