Medication errors related to computerized order entry for children.
Walsh KE, Adams WG, Bauchner H, et al. Pediatrics. 2006;118:1872-1879.
This retrospective study, conducted in a children's hospital with a widely used commercial
computerized provider order entry
(CPOE) system, used active surveillance to examine the frequency and types of medication errors associated with CPOE. The authors found an overall rate of medication errors of 53.9 per 1000 patient-days, similar to a
; only 19% of these were deemed to be related to design features of the CPOE system. These included errors in selecting medications from drop-down menus and selecting incorrect order sets. None of the CPOE-related adverse drug events (ADEs) resulted in patient injury. While
has raised concern that implementation of CPOE systems may result in more ADEs,
supports this study's conclusion that careful attention to CPOE design features may ameliorate the risk of ADEs.
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The relationship between computerized physician order entry and pediatric adverse drug events: a nested matched case-control study.
Yu F, Salas M, Kim YI, Menachemi N. Pharmacoepidemiol Drug Saf. 2009;18:751-755.
Antimicrobial prescription errors in hospitalized children: role of antimicrobial stewardship program in detection and intervention.
Di Pentima MC, Chan S, Eppes SC, Klein JD. Clin Pediatr (Phila). 2009;53:715-723e1.
Effect of computerized provider order entry with clinical decision support on adverse drug events in the long-term care setting.
Gurwitz JH, Field TS, Rochon P, et al. J Am Geriatr Soc. 2008;56:2225-2233.
Adverse drug event rates in six community hospitals and the potential impact of computerized physician order entry for prevention.
Hug BL, Witkowski DJ, Sox CM, et al. J Gen Intern Med. 2010;25:31-38.
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Epidemiology of Errors and Adverse Events
Approach to Improving Safety
Computerized Provider Order Entry (CPOE)
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