The Joint Commission recognizes potential overuse of diagnostic imaging, particularly computed tomographic (CT) scans, to be a patient safety risk due to excess radiation exposure. This study sought to determine whether low-dose whole-body CT (WBCT), which exposes the patient to less radiation, has similar accuracy to standard-dose WBCT. A cohort of over 1,000 patients with suspected blunt trauma were prospectively recruited; half received standard-dose WBCT and the other half received low-dose WBCT.  The authors found that use of low-dose WBCT did not increase risk of missed injury diagnosis, while reducing median radiation exposure by almost half.