This systematic review is an update of prior research characterizing the evidence base on team effectiveness in healthcare organizations. The review analyzed 297 publications focused on three types of interventions: (1) training, including crew resource management, TeamSTEPPS and simulations, (2) tools, including SBARs and checklists, and (3) organizational (re)designs, which involves intervening in structures which lead to improved team functioning (such as changing the physical environment or altering roles/responsibilities). The authors found that existing evidence base is limited to certain interventions, settings (primarily acute care), and outcomes (primarily non-technical skills). The authors call for more longitudinal research, particularly examining team functioning outside the hospital setting.