Patients frequently use search engines to find information about symptoms, health conditions, and medications and are now turning to AI chatbots such as ChatGPT. In this study, ChatGPT-3.5 was prompted with questions patients may ask about the top 20 prescribed medications, such as side effects or interactions. Responses were rated for completeness and accuracy. Ninety-seven percent were completely or mostly accurate, and 81% were comprehensively complete.