Journal Article
Study

Active surveillance of vaccine safety: a system to detect early signs of adverse events.

Davis RL, Kolczak M, Lewis E, et al. Epidemiology (Cambridge, Mass.). 2005;16:336-41.

Given a lack of effective systems to detect adverse events with new vaccine administration, this study used existing data to compare event rates after changing to new rotavirus and diphtheria-pertussis-tetanus (DPT) vaccines. The surveillance system accurately captured adverse events, which supports the viability of similar systems in monitoring new vaccine safety.