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PSNet: Patient Safety Network
Journal Article

Adverse drug events in hospitalized cardiac patients.

Fanikos J, Cina JL, Baroletti S, et al. The American journal of cardiology. 2007;100:1465-9.

This study noted two adverse drug events (ADEs) per 100 patient admissions in hospitalized cardiac patients. Preventable ADEs most frequently occurred during medication administration, and cardiovascular agents and anticoagulants were the most common drug classes involved. Interestingly, the most preventable ADEs occurred between 7:00 AM and 9:00 AM, during handoffs between nurses at shift change. The authors advocate for prevention strategies around medication administration and nursing shift changes to reduce the potential for errors.