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The burden of opioid-related adverse drug events on hospitalized previously opioid-free surgical patients.
March 10, 2021
Urman RD, Seger DL, Fiskio JM, et al. J Patient Saf. 2021;17(2):e76-e83.
Harm from opioids is a widely recognized patient safety issue, and potential harm associated with short-term use is a growing area of concern. This analysis of a previously opioid-free surgical population identified a high rate of potential opioid-related adverse drug events (ORADEs); risk was strongly associated with route and duration of post-operative opioid administration. The presence of an ORADE was associated with longer postoperative length of stay, higher hospitalization costs, lower odds of discharge home, and higher odds of death.
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