Clinical impact of medication review and deprescribing in older inpatients: a systematic review and meta-analysis.
Carollo M, Crisafulli S, Vitturi G, et al. Clinical impact of medication review and deprescribing in older inpatients: a systematic review and meta‐analysis. J Am Geriatr Soc. 2024;72(10):3219-3238. doi:10.1111/jgs.19035.
Potentially inappropriate medications (PIM) and polypharmacy in older adults contribute to increased risk of hospitalization. This systematic review and meta-analysis evaluated the impact of medication review and deprescribing interventions on hospitalized older adults' clinical outcomes including mortality and hospitalizations. Medication review and deprescribing resulted in a slight reduction of rehospitalizations with no impact on mortality.