Clinical impact of medication review and deprescribing in older inpatients: a systematic review and meta-analysis.
Potentially inappropriate medications (PIM) and polypharmacy in older adults contribute to increased risk of hospitalization. This systematic review and meta-analysis evaluated the impact of medication review and deprescribing interventions on hospitalized older adults' clinical outcomes including mortality and hospitalizations. Medication review and deprescribing resulted in a slight reduction of rehospitalizations with no impact on mortality.