Journal Article

A computer alert system to prevent injury from adverse drug events: development and evaluation in a community teaching hospital.

Raschke RA, Gollihare B, Wunderlich TA, et al. JAMA. 2003;280.

An alert system triggered by 37 drug-specific adverse events was programmed into a 650-bed hospital information system. The investigators found that 53% of the alerts were valid ("true positives") and that 44% of these had been unrecognized by the prescribing physicians prior to notification. The authors conclude that computer alert systems can help prevent a wide range of adverse drug events. This study was one of the first to support the use of trigger systems to recognize and help prevent medication errors.