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PSNet: Patient Safety Network
Journal Article
Study

Concealed renal insufficiency and adverse drug reactions in elderly hospitalized patients.

Corsonello A, Pedone C, Corica F, et al. Archives of internal medicine. 2005;165:790-5.

This study reviewed data on 11,687 patients to explore the relationship between suboptimal kidney function and adverse drug reactions (ADRs) in older inpatients. Hydrosoluble medications, including diuretics, digitalis, angiotensin-converting enzyme inhibitors, and hypoglycemic agents, posed the greatest risk of ADRs to this patient population.