Journal Article
Review

The cost of opioid–related adverse drug events.

Kane-Gill SL, Rubin EC, Smithburger PL, et al. Journal of pain & palliative care pharmacotherapy. 2014;28:282-93.

Opioids are particularly dangerous medications that may lead to various adverse drug events including nausea, vomiting, respiratory depression, and death. This review defined the substantial economic impact of adverse events resulting from opioids, finding health care costs increased 7% to 47% for patients that experienced an opioid–related adverse event.