Journal Article

Evaluation of medication-related clinical decision support alert overrides in the intensive care unit.

Wong A; Amato MG; Seger DL; Slight SP; Beeler PE; Dykes PC; Fiskio JM; Silvers ER; Orav EJ; Eguale T; Bates DW.

This retrospective study reviewed more than 47,000 overridden medication alerts and found that the vast majority of overrides were clinically appropriate and did not cause harm. From this sample, 7 adverse drug events were identified, and these events were more likely when the alerts were overridden in error. This study demonstrates the challenge of identifying clinically important alerts in a setting where alert fatigue is common.