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Filling the gaps on the Institute for Safe Medication Practices (ISMP) Do Not Crush List for Immediate-release Products

Uttaro E, Zhao F, Schweighardt A. Int J Pharm Compd. 2021;25(5):364-371. 

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December 22, 2021

Uttaro E, Zhao F, Schweighardt A. Int J Pharm Compd. 2021;25(5):364-371. 

Medication administration, particularly when it involves drug formulation manipulation, is a complex process. This study analyzed the products included on the Institute for Safe Medication Practices’ (ISMP) ‘Do Not Crush List’ and found that many presented no risk or low risk for crushing. The authors provide recommendations for clinicians to aid in clinical decision-making regarding crushing, such as suitable personal protective equipment and prompt administration.