In many clinical areas such as primary care, advanced practice providers (APP), including nurse practitioners and physician assistants, are licensed to practice independent of physician supervision. This study evaluated the rate of chemotherapy prescribing adverse events and near misses submitted to the institutional reporting system for both oncology physicians and APPs. The odds of a reported event were higher for physicians than APPs. However, given the voluntary and subjective nature of event reporting, the study was unable to determine if actual patient harm occurred in either group.