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PSNet: Patient Safety Network
Journal Article

Impact of non-interruptive medication laboratory monitoring alerts in ambulatory care.

Lo HG, Matheny ME, Seger DL, et al. Journal of the American Medical Informatics Association : JAMIA. 2009;16:66-71.

"Alert fatigue" refers to the tendency of clinicians to ignore safety alerts—for example, warnings about potential drug interactions—if alerts are too frequent or perceived to be clinically irrelevant. However, in this study, less intrusive alerts that did not require physician response were not effective at encouraging use of recommended laboratory monitoring.