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Improving the specificity of drug-drug interaction alerts: Can it be done?

Reese T, Wright A, Liu S, et al. Improving the specificity of drug-drug interaction alerts: Can it be done? Am J Health Syst Pharm. Epub 2022 Feb 10. doi: 10.1093/ajhp/zxac045

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April 6, 2022
Reese T, Wright A, Liu S, et al. Am J Health Syst Pharm. 2022;Epub Feb 10.

Computerized decision support alerts for drug-drug interactions are commonly overridden by clinicians. This study examined fifteen well-known drug-drug interactions and identified risk factors that could reduce risk in the majority of interactions (e.g., medication order timing, medication dose, and patient factors).