The influence that electronic prescribing has on medication errors and preventable adverse drug events: an interrupted time-series study.

Jasperien van Doormaal; Patricia M L A van den Bemt; Rianne J Zaal; Antoine C G Egberts; Bertil W Lenderink; Jos G W Kosterink; Flora M Haaijer-Ruskamp; Peter G M Mol

Study

The influence that electronic prescribing has on medication errors and preventable adverse drug events: an interrupted time-series study.

December 2, 2009

van Doormaal J, van den Bemt PMLA, Zaal RJ, et al. J Am Med Inform Assoc. 2009;16(6):816-25.

View more articles from the same authors.

A decision support system combined with computerized provider order entry significantly reduced incorrect prescriptions, but the incidence of clinical adverse drug events was unchanged.

PubMed citation

Available at

Free full text

Related Resources From the Same Author(s)

Reliability of the assessment of preventable adverse drug events in daily clinical practice.

April 2, 2008

Preventable and non-preventable adverse drug events in hospitalized patients: a prospective chart review in the Netherlands.

November 9, 2011

Comparison of potential risk factors for medication errors with and without patient harm.

August 18, 2010

Medication errors: the impact of prescribing and transcribing errors on preventable harm in hospitalised patients.

March 4, 2009

Comparison of methods for identifying patients at risk of medication-related harm.

July 21, 2010

Frequency of and risk factors for preventable medication-related hospital admissions in the Netherlands.

October 1, 2008

Effect of medication reconciliation with and without patient counseling on the number of pharmaceutical interventions among patients discharged from the hospital.

August 19, 2009

Anticoagulant medication errors in hospitals and primary care: a cross-sectional study.

November 14, 2018

The effect of prescriber education on medication-related patient harm in the hospital: a systematic review.

March 8, 2017

Self-reported uptake of recommendations after dissemination of medication incident alerts.

August 22, 2012

The impact of type of manual medication cart filling method on the frequency of medication administration errors: a prospective before and after study.

February 23, 2011

Classification of medication incidents associated with information technology.

October 9, 2013

Medication administration errors in nursing homes using an automated medication dispensing system.

July 15, 2009

The effect of a clinical pharmacist-led training programme on intravenous medication errors: a controlled before and after study.

April 2, 2014

May 26, 2021

Medication reconciliation performed by pharmacy technicians at the time of preoperative screening.

July 29, 2009

Experiences with Lean Six Sigma as improvement strategy to reduce parenteral medication administration errors and associated potential risk of harm.

July 26, 2017

Drug administration errors in an institution for individuals with intellectual disability: an observational study.

August 29, 2007

Prescribing errors with low-molecular-weight heparins.

October 13, 2021

Preventable hospital admissions related to medication (HARM): cost analysis of the HARM study.

March 1, 2011

Effect of warning symbols in combination with education on the frequency of erroneously crushing medication in nursing homes: an uncontrolled before and after study.

September 7, 2016

The effect of computerized physician order entry on medication prescription errors and clinical outcome in pediatric and intensive care: a systematic review.

April 15, 2009

Association between workarounds and medication administration errors in bar-code-assisted medication administration in hospitals.

April 25, 2018

Prevalence of medication transfer errors in nephrology patients and potential risk factors.

November 6, 2019

The effect of medication reconciliation via a patient portal on medication discrepancies: a randomized noninferiority study.

January 26, 2022

The effect of a transitional pharmaceutical care program on the occurrence of ADEs after discharge from hospital in patients with polypharmacy.

April 27, 2022

Effect of a pharmacy-based centralized intravenous admixture service on the prevalence of medication errors: a before-and-after study.

August 10, 2022

Effect of medication reconciliation on patient reported potential adverse events after hospital discharge.

September 8, 2021

Effect of automated unit dose dispensing with barcode scanning on medication administration errors: an uncontrolled before-and-after study.

December 1, 2021

Risk factors for clinically relevant deviations in patients' medication lists reported by patients in personal health records: a prospective cohort study in a hospital setting.

March 2, 2022

Differences in medication reconciliation interventions between six hospitals: a mixed method study.

June 29, 2022

Clinical pharmacy interventions in paediatric electronic prescriptions.

May 15, 2013

Time-dependent drug–drug interaction alerts in care provider order entry: software may inhibit medication error reductions.

December 2, 2009

Detectability of medication errors with a STOPP/START-based medication review in older people prior to a potentially preventable drug-related hospital admission.

December 21, 2022

Maternal mortality: near-miss events in middle-income countries, a systematic review.

November 24, 2021

Factors associated with workarounds in barcode-assisted medication administration in hospitals.

August 26, 2020

'Providing good and comfortable care by building a bond of trust': nurses views regarding their role in patients' perception of safety in the intensive care unit.

November 11, 2015

Cognitive diagnostic error in internal medicine.

April 24, 2013

Prescribing errors in post-COVID-19 patients: prevalence, severity, and risk factors in patients visiting a post-COVID-19 outpatient clinic.

March 23, 2022

Systematic literature review on the effectiveness and safety of paediatric hospital-at-home care as a substitute for hospital care.

May 17, 2023

Do patients' disruptive behaviours influence the accuracy of a doctor's diagnosis? A randomised experiment.

March 23, 2016

The use of "lives saved" measures in nurse staffing and patient safety research: statistical considerations.

March 30, 2011

Safety perceptions of health care leaders in 2 Canadian academic acute care centers.

June 7, 2017

Improving medical residents’ self-assessment of their diagnostic accuracy: does feedback help?

February 2, 2022

Why do doctors make mistakes? A study of the role of salient distracting clinical features.

December 11, 2013

January 19, 2011

Do malpractice claim clinical case vignettes enhance diagnostic accuracy and acceptance in clinical reasoning education during GP training?

September 20, 2023

How would final-year medical students perform if their skill-based prescription assessment was real life?

February 22, 2023

The $17.1 billion problem: the annual cost of measurable medical errors.

April 20, 2011

Information technology cannot guarantee patient safety.

May 2, 2007

Validation of hospital administrative dataset for adverse event screening.

June 30, 2010

Safety of telephone triage in general practitioner cooperatives: do triage nurses correctly estimate urgency?

June 27, 2007

Exposure to media information about a disease can cause doctors to misdiagnose similar-looking clinical cases.

March 12, 2014

Effect of availability bias and reflective reasoning on diagnostic accuracy among internal medicine residents.

October 6, 2010

2019 Novel Coronavirus (COVID-19) pandemic: built environment considerations to reduce transmission.

May 6, 2020

The relationship between inpatient cardiac surgery mortality and nurse numbers and educational level: analysis of administrative data.

April 8, 2009

Sleep and errors in a group of Australian hospital nurses at work and during the commute.

November 19, 2008

Adverse effects of the Medicare PSI-90 hospital penalty system on revenue-neutral hospital-acquired conditions.

September 5, 2018

Patient safety and acute care medicine: lessons for the future, insights from the past.

March 24, 2010

Effect on diagnostic accuracy of cognitive reasoning tools for the workplace setting: systematic review and meta-analysis.

September 14, 2022

Review: bringing patient safety to the forefront through structured computerisation during clinical handover.

September 22, 2010

Where are my instruments? Hazards in delivery of surgical instruments.

August 10, 2016

Understanding handling of drug safety alerts: a simulation study.

May 5, 2010

Turning off frequently overridden drug alerts: limited opportunities for doing it safely.

May 21, 2008

Medication errors in hospitals: a literature review of disruptions to nursing practice during medication administration.

September 23, 2015

Team-based approach to improving medication reconciliation rates in family medicine residency clinics.

October 7, 2020

Validating a decision tree for serious infection: diagnostic accuracy in acutely ill children in ambulatory care.

August 19, 2015

Multidisciplinary team training in a simulation setting for acute obstetric emergencies: a systematic review.

May 19, 2010

Patient harm in general surgery--a prospective study.

April 4, 2007

The relationship between patient safety culture and the implementation of organizational patient safety defences at emergency departments.

May 19, 2010

Evaluating the medication process in the context of CPOE use: the significance of working around the system.

May 25, 2011

Overriding of drug safety alerts in computerized physician order entry.

January 11, 2006

Effect of a comprehensive surgical safety system on patient outcomes.

November 24, 2010

Adverse events following an emergency department visit.

February 28, 2007

Nurse staffing and education and hospital mortality in nine European countries: a retrospective observational study.

April 23, 2014

Nurse interrupted: development of a realistic medication administration simulation for undergraduate nurses.

August 26, 2015

Is culture associated with patient safety in the emergency department? A study of staff perspectives.

April 23, 2014

Self-reported patient safety competence among new graduates in medicine, nursing and pharmacy.

January 9, 2013

Same system, different outcomes: comparing the transitions from two paper-based systems to the same computerized physician order entry system.

September 24, 2008

Effect of US Drug Enforcement Administration's rescheduling of hydrocodone combination analgesic products on opioid analgesic prescribing.

November 23, 2016

Multi-professional simulation-based team training in obstetric emergencies for improving patient outcomes and trainees' performance

February 17, 2021

The impact of introducing automated dispensing cabinets, barcode medication administration, and closed-loop electronic medication management systems on work processes and safety of controlled medications in hospitals: a systematic review.

April 7, 2021

Incidents and errors in neonatal intensive care: a review of the literature.

September 5, 2007

Signs and symptoms to determine if a patient presenting in primary care or hospital outpatient settings has COVID-19 disease.

July 29, 2020

Investigating US medical students' motivation to respond to lapses in professionalism.

October 3, 2018

Prognosis of undiagnosed chest pain: linked electronic health record cohort study.

April 19, 2017

Association of work environment with missed and rushed care: tasks among care aides in nursing homes.

March 11, 2020

The H-PEPSS: an instrument to measure health professionals' perceptions of patient safety competence at entry into practice.

June 13, 2012

Integrating patient safety into health professionals' curricula: a qualitative study of medical, nursing and pharmacy faculty perspectives.

February 19, 2014

An educational intervention to enhance nurse leaders' perceptions of patient safety culture.

August 3, 2005

Canadian Association of University Surgeons' Annual Symposium. Surgical simulation: the solution to safe training or a promise unfulfilled?

September 5, 2012

A 6-year thematic review of reported incidents associated with cardiopulmonary resuscitation calls in a United Kingdom hospital.

April 27, 2022

Clinical reasoning in the context of active decision support during medication prescribing.

April 5, 2017

Safety incidents in family medicine.

September 28, 2011

Patient–pharmacist communication during a post-discharge pharmacist home visit.

April 10, 2019

Economic impact of medication error: a systematic review.

May 17, 2017

Creating the web-based intensive care unit safety reporting system.

September 28, 2005

Patient safety in primary allied health care: what can we learn from incidents in a Dutch exploratory cohort study?

November 16, 2011

'Not another safety culture survey': using the Canadian patient safety climate survey (Can-PSCS) to measure provider perceptions of PSC across health settings.

November 13, 2013

Patient safety, satisfaction, and quality of hospital care: cross sectional surveys of nurses and patients in 12 countries in Europe and the United States.

April 4, 2012

Related Resources

Exploring the impact of safety culture on incident reporting: lessons learned from machine learning analysis of NHS England staff survey and incident data.

August 30, 2023

Human factors and safety analysis methods used in the design and redesign of electronic medication management systems: a systematic review.

May 17, 2023

Indication documentation and indication-based prescribing within electronic prescribing systems: a systematic review and narrative synthesis.

April 5, 2023

Perspectives on Safety

Annual Perspective

Technology as a Tool for Improving Patient Safety

March 29, 2023

WebM&M Cases

Overdose of Gabapentin and Oxycodone in a Patient with End-Stage Renal Disease: A Case for Appropriate Interruptive Drug-Disease Alerts.

February 1, 2023

Electronic prescribing systems in hospitals to improve medication safety: a multi-methods research programme.

December 21, 2022

The electronic prescribing of subcutaneous infusions: a before-and-after study assessing the impact upon patient safety and service efficiency.

June 15, 2022

The potential for leveraging machine learning to filter medication alerts.

May 4, 2022

The development and piloting of the Ambulatory Electronic Health Record Evaluation Tool: lessons learned.

March 17, 2021

ASHP national survey of pharmacy practice in hospital settings: prescribing and transcribing-2019.

September 30, 2020

The MedSafer Study: a controlled trial of an electronic decision support tool for deprescribing in acute care.

July 31, 2019

How often do prescribers include indications in drug orders? Analysis of 4 million outpatient prescriptions.

July 10, 2019

Avoiding chemotherapy prescribing errors: analysis and innovative strategies.

February 13, 2019

Systematic review of computerized prescriber order entry and clinical decision support.

February 6, 2019

Perspective

Integrating Multiple Medication Decision Support Systems: How Will We Make It All Work?

May 1, 2018

Impact of a commercial order entry system on prescribing errors amenable to computerised decision support in the hospital setting: a prospective pre–post study.

April 18, 2018

Case not closed: prescription errors 12 years after computerized physician order entry implementation.

January 31, 2018

Sustained user engagement in health information technology: the long road from implementation to system optimization of computerized physician order entry and clinical decision support systems for prescribing in hospitals in England.

November 1, 2017

Outpatient CPOE orders discontinued due to 'erroneous entry': prospective survey of prescribers' explanations for errors.

August 16, 2017

Prescription errors related to the use of computerized provider order-entry system for pediatric patients.

June 14, 2017

Opioid Epidemic & Health IT

May 18, 2016

The frequency of inappropriate nonformulary medication alert overrides in the inpatient setting.

April 6, 2016

Implementation of a custom alert to prevent medication-timing errors associated with computerized prescriber order entry.

September 16, 2015

Frequency and severity of parenteral nutrition medication errors at a large children's hospital after implementation of electronic ordering and compounding.

August 19, 2015

Non-intercepted dose errors in prescribing antineoplastic treatment: a prospective, comparative cohort study.

March 11, 2015

Impact of a clinical decision support system for high-alert medications on the prevention of prescription errors.

February 11, 2015

Computerised physician order entry-related medication errors: analysis of reported errors and vulnerability testing of current systems.

January 28, 2015

Impact of a warning CPOE system on the inappropriate pill splitting of prescribed medications in outpatients.

January 21, 2015

Differences of reasons for alert overrides on contraindicated co-prescriptions by admitting department.

December 17, 2014

Hardwiring patient blood management: harnessing information technology to optimize transfusion practice.

October 22, 2014

See More About The Topic

Health Care Providers

Quality and Safety Professionals

Information Professionals

Pharmacy

Ordering/Prescribing Errors

The influence that electronic prescribing has on medication errors and preventable adverse drug events: an interrupted time-series study.

Connect With Us

Sign up for Email Updates

Agency for Healthcare Research and Quality

The influence that electronic prescribing has on medication errors and preventable adverse drug events: an interrupted time-series study.

Connect With Us

Sign up for Email Updates

Agency for Healthcare Research and Quality

PSNet Log in

Submit Your Innovations

Continue as a Guest

Continue Logged In

Submit Your Innovations

Continue as a Guest

Continue logged in

New Users to the PSNet site