Journal Article
Study

Major congenital malformations after first-trimester exposure to ACE inhibitors.

Cooper WO, Hernandez-Diaz S, Arbogast PG, et al. New England Journal of Medicine. 2006;354.

This U.S. Food and Drug Administration (FDA)– and AHRQ–funded study documents the possibility of adverse effects on the fetus when mothers take angiotensin-converting enzyme (ACE) inhibitors during the first trimester of pregnancy.