Remote or virtual patient care was an increasingly common strategy during the COVID-19 pandemic to keep patients safe and ensure adequate inpatient resources for patients unable to be cared for virtually. In this study, hospital physicians, pharmacists, and nurses described medication challenges associated with patients receiving virtual care (i.e., hospital-level care at home or hotel). Participants described challenges with lack of clarity on who is responsible for the patient's usual home medications, disruptions to typical workflow, and difficulties with transition from inpatient to virtual care.