This study is the second phase of the United Kingdom's Safer Patients Initiative (SPI), a large-scale effort to improve patient safety through multifaceted interventions and an independent evaluation. Similar to the first phase study, this one demonstrated little added benefit of SPI on key safety outcomes in 20 hospitals, though overall safety did improve. An accompanying editorial [see link below] discusses the study findings and emphasizes the continued need to run toward science rather than away from it in evaluating quality improvement efforts.