Patient participation in their own care is promoted as an important safety strategy. In this study, participants were asked to rate the importance and reasonableness of eight safety behaviors promoted by healthcare professionals: bringing medications to office visits, confirming medications at home, managing medication refills, using patient portals, organizing medications, checking medications, getting help, and knowing medications. Confirming medications was rated as the most important behavior, and knowing medications was rated as most reasonable. Using patient portals was rated as lowest in importance and reasonableness. Participants 65 and older reported higher importance and reasonableness of all eight safety behaviors than younger participants.