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PSNet: Patient Safety Network
Journal Article

Potential utility of data-mining algorithms for early detection of potentially fatal/disabling adverse drug reactions: a retrospective evaluation.

Hauben M, Reich L. Journal of clinical pharmacology. 2005;45:378-84.

The authors compare the efficacy of two data-mining strategies with traditional methods in flagging potential adverse drug reactions. While the tested algorithms showed promise to improve existing pharmacovigilance strategies, no clear benefit was demonstrated over traditional methods for the majority of drug-event combinations.