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Prehospital naloxone and emergency department adverse events: a dose-dependent relationship.

Maloney LM, Alptunaer T, Coleman G, et al. Prehospital naloxone and emergency department adverse events: a dose-dependent relationship. J Emerg Med. Epub 2020 Sept 26. doi: 10.1016/j.jemermed.2020.07.009

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November 25, 2020
Maloney LM, Alptunaer T, Coleman G, et al. J Emerg Med. 2020;59(6):872-883.

Naloxone administration in inpatient and outpatient settings is used to mitigate the effects of opioid overdose. This study, conducted at one academic medical center, found that an increasing number prehospital naloxone doses for suspected opioid overdose was significantly associated with an increased likelihood of adverse events (AEs) in the emergency department (ED).

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Maloney LM, Alptunaer T, Coleman G, et al. Prehospital naloxone and emergency department adverse events: a dose-dependent relationship. J Emerg Med. Epub 2020 Sept 26. doi: 10.1016/j.jemermed.2020.07.009