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PSNet: Patient Safety Network
Journal Article

Prehospital naloxone and emergency department adverse events: a dose-dependent relationship.

Maloney LM, Alptunaer T, Coleman G, et al. J Emerg Med. 2020;Epub Sep 26.

Naloxone administration in inpatient and outpatient settings is used to mitigate the effects of opioid overdose. This study, conducted at one academic medical center, found that an increasing number prehospital naloxone doses for suspected opioid overdose was significantly associated with an increased likelihood of adverse events (AEs) in the emergency department (ED).