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Prevalence of adverse drug combinations in a large post-mortem toxicology database.
Launiainen T, Vuori E, Ojanperä I. Prevalence of adverse drug combinations in a large post-mortem toxicology database. Int J Legal Med. 2009;123(2):109-15. doi:10.1007/s00414-008-0261-3.
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February 23, 2009
Launiainen T, Vuori E, Ojanperä I. Int J Legal Med. 2009;123(2):109-15.
This study examined more than 37,000 post-mortem cases and discovered that 0.71% were associated with potentially severe drug–drug interactions. The most common medications implicated were those causing serotonin syndrome and combinations of atrioventricular nodal agents (e.g., beta blockers and calcium-channel blockers).
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