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November 28, 2007

Reasons provided by prescribers when overriding drug–drug interaction alerts.

Grizzle AJ, Mahmood MH, Ko Y, et al. Reasons provided by prescribers when overriding drug-drug interaction alerts. The American journal of managed care. 2007;13(10):573-8.

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Grizzle AJ, Mahmood MH, Ko Y, et al. The American journal of managed care. 2007;13:573-8.

This study discovered that more than 70% of overrides identified in a computerized provider order entry (CPOE) system were for critical drug–drug interactions. The authors also point out that 53% of providers offered no clinical justification for such overrides, raising questions about the system’s need for redesign.

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Grizzle AJ, Mahmood MH, Ko Y, et al. Reasons provided by prescribers when overriding drug-drug interaction alerts. The American journal of managed care. 2007;13(10):573-8.