Serious adverse drug events reported to the Food and Drug Administration, 1998-2005.
Moore TJ, Cohen MR, Furberg CD. Serious adverse drug events reported to the Food and Drug Administration, 1998-2005. Arch Intern Med. 2007;167(16):1752-9.
Voluntarily reported adverse drug events increased markedly from 1998-2005, with a small proportion of drugs accounting for a disproportionate share of adverse events.