Journal Article
Study

Tablet-splitting: a common yet not so innocent practice.

Verrue C, Mehuys E, Boussery K, et al. Journal of advanced nursing. 2011;67:26-32.

Pharmacists and patients commonly split pills in order to increase dose flexibility and make pills easier to swallow. However, this study found that splitting pills resulted in unpredictable dose deviations, which could lead to underdosing or overdosing.