Targeted implementation of the Comprehensive Unit-Based Safety Program through an assessment of safety culture to minimize
central line-associated bloodstream infections.
The Comprehensive Unit-based Safety Program (CUSP) reduced central line–associated bloodstream infections (CLABSI) in intensive care units nationwide, but its effectiveness varies among settings. This analysis found that units with a strong safety culture had greater success in lowering CLABSI with CUSP implementation than units with a worse safety culture. The authors suggest addressing a unit's safety culture prior to implementing CUSP to augment its impact.