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PSNet: Patient Safety Network
Journal Article
Study

Time trends in pulmonary embolism in the United States: evidence of overdiagnosis.

Wiener RS, Schwartz LM, Woloshin S. Archives of internal medicine. 2011;171:831-7.

Since the introduction of new diagnostic technologies in the late 1990s, pulmonary embolism diagnoses have increased, but mortality from pulmonary embolisms has not decreased. This combination of findings likely represents overdiagnosis—either due to false-positive diagnoses or detection (and treatment) of clinically insignificant clots.