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August 7, 2024 Weekly Issue

PSNet highlights the latest patient safety literature, news, and expert commentary, including Weekly Updates, WebM&M, and Perspectives on Safety. The current issue highlights what's new this week in patient safety literature, news, conferences, reports, and more. Past issues of the PSNet Weekly Update are available to browse. WebM&M presents current and past monthly issues of Cases & Commentaries and Perspectives on Safety.

This Week’s Featured Articles

Farhat H, Alinier G, Tluli R, et al. J Patient Saf. 2024;20(5):330-339.
Artificial intelligence (AI) is increasingly used to interpret and summarize large volumes of free text. This novel study used AI techniques natural language processing (NLP), machine learning (ML), and sentiment analysis (SA) to learn more about why patients decline transport to hospital after receiving prehospital emergency care. Three-quarters of patients who declined transport said they “felt better.” Of the remaining patients, negative sentiments, such as "afraid" and "hospital," were observed.
Heath M, Bernstein SJ, Paje D, et al. Jt Comm J Qual Patient Saf. 2024;50(8):591-600.
Quality improvement and patient safety projects can be costly to implement. This article describes the cost-effectiveness of the Michigan Hospital Medicine Safety Consortium (HMS) quality improvement project to reduce peripherally inserted central catheter (PICC) complications. PICC complications decreased significantly over the 7-year project, and each participating hospital averaged $932,000 in cost-offset. The HMS PICC Use Initiative is highlighted on the PSNet Innovations page.
Kim H-J, Ko R-E, Lim SY, et al. JAMA Netw Open. 2024;7(7):e2422823.
Early detection and management of sepsis is an important patient safety target. This systematic review included 22 studies and examined the use of sepsis alert systems in the Emergency Department (ED) on patient outcomes. The researchers found that sepsis alert systems were associated with reduced risk of mortality and decreased length of stay, as well as increased adherence to sepsis management guidelines, such as timely administration of antibiotics.
Rzewnicki D, Kanvinde A, Gillespie S, et al. JAMIA Open. 2024;7(3):ooae042.
Patient misidentification can lead to serious patient safety risks. In this study, conducted at one pediatric hospital system, the presence of a patient photograph in the electronic health record (EHR) associated with a 40% reduction in the odds of retract-and-reorder events, a surrogate measure of wrong-patient order entry
Johnson CT, Hessels AJ. Am J Infect Control. 2024;52(9):1102-1104.
A positive safety climate is associated with greater adherence to patient safety practices. This multi-site study evaluated the association of a negative safety climate with observed and reported standard precaution (SP) adherence. A perceived negative safety climate was associated with poor adherence to several, but not all, SP practices.
Farhat H, Alinier G, Tluli R, et al. J Patient Saf. 2024;20(5):330-339.
Artificial intelligence (AI) is increasingly used to interpret and summarize large volumes of free text. This novel study used AI techniques natural language processing (NLP), machine learning (ML), and sentiment analysis (SA) to learn more about why patients decline transport to hospital after receiving prehospital emergency care. Three-quarters of patients who declined transport said they “felt better.” Of the remaining patients, negative sentiments, such as "afraid" and "hospital," were observed.
Heath M, Bernstein SJ, Paje D, et al. Jt Comm J Qual Patient Saf. 2024;50(8):591-600.
Quality improvement and patient safety projects can be costly to implement. This article describes the cost-effectiveness of the Michigan Hospital Medicine Safety Consortium (HMS) quality improvement project to reduce peripherally inserted central catheter (PICC) complications. PICC complications decreased significantly over the 7-year project, and each participating hospital averaged $932,000 in cost-offset. The HMS PICC Use Initiative is highlighted on the PSNet Innovations page.
Adamovic I, Dahlem P, Brachmann J. Int J Qual Health Care. 2024;36(3):mzae064.
New or redesigned facilities may introduce safety challenges not previously experienced. In this study, adverse events (AE) were measured 6 months before and after the opening of a new hospital. The rate of AE increased in the new hospital during the first 6 months, highlighting the importance of proactive identification of unsafe situations and close monitoring.
Flynn AJ, Mieure KD, Myers C. Am J Health Syst Pharm. 2024;81(14):622-633.
There are many strategies to improve medication safety, such as tall man lettering, but serious errors still occur. This study describes a new method of ensuring the appropriate medication is selected by requiring users to type just enough characters of the medication name to uniquely identify a single name. Results show as few as 4 characters may be needed to identify a single name, but substantial research is still required, including in real-world settings.
Iyer RS, Dave N, Du T, et al. Paediatr Anaesth. 2024;34(9):958-969.
Patient safety organizations (PSOs), such as Wake Up Safe, can aggregate data and share lessons from rare adverse events. This article describes Wake Up Safe in the United States and similar pediatric anesthesia PSOs implemented in Australia-New Zealand, India, and Singapore. Barriers, enablers, and potential collaborations between nations are described.
McCulloch P. BMJ Qual Saf. 2024;33(8):539-542.
Human factors and ergonomics are widely used in high-risk industries, such as aviation, to promote safety. This article summarizes ongoing challenges in the use of human factors and ergonomics to address patient safety threats in the UK’s National Health Service (NHS) such as organizational pressures or lack of leadership support.
Zeng A, Houssami N, Noguchi N, et al. Breast Cancer Res Treat. 2024;207(1):1-13.
Artificial intelligence (AI) is increasingly used in radiology to support cancer screening. This systematic review examined the frequency of errors when using artificial intelligence for reading breast screening mammograms. Based on seven included studies, the researchers found that the test performance of AI algorithms used to read screening mammograms varied, and AI errors were infrequently reported.
Appelbaum RD, Puzio TJ, Bauman Z, et al. J Trauma Acute Care Surg. 2024;97(2):305-314.
Standardized handoffs are known to improve patient outcomes in many clinical settings. This review analyzed research on standardized handoffs in acute care surgery, which includes trauma, emergency general surgery, and surgical critical care. Ten studies were identified but the heterogeneity of outcomes made it difficult to compare the various studies. Based on the review, the authors conditionally recommend use of a standardized handoff in perioperative interactions, between emergency medical services and trauma team, and between wards and intensive care units.
Kim H-J, Ko R-E, Lim SY, et al. JAMA Netw Open. 2024;7(7):e2422823.
Early detection and management of sepsis is an important patient safety target. This systematic review included 22 studies and examined the use of sepsis alert systems in the Emergency Department (ED) on patient outcomes. The researchers found that sepsis alert systems were associated with reduced risk of mortality and decreased length of stay, as well as increased adherence to sepsis management guidelines, such as timely administration of antibiotics.
Johns E, Alkanj A, Beck M, et al. Eur J Hosp Pharm. 2023;31(4):289-294.
Artificial intelligence (AI) is a promising approach to improving patient safety. This review aimed to summarize research on integration of AI to detect inappropriate medication ordering in hospitals. The size, aim, and AI model varied widely, preventing comparisons across studies. Further research should involve clinical pharmacists as they will be the end users of these AI tools.

Washington DC: National Academies of Sciences, Engineering and Medicine; July 25, 2024.

Digital health is emerging as a primary technological component of health care. This workshop explored policy and research topics  on the role of artificial intelligence (AI) in diagnosis. Participants examined steps to improve the development and deployment of AI algorithms that ensure the equitable, secure, and safe diagnostic use of the technology.

ISMP Medication Safety Alert! Acute Care. July 11, 2024;29;(14):1-3; July 25, 2024;29(15):1-5.

Psychological safety is core to the effective sharing of operational and clinical concerns. This two-part newsletter article discusses tactics to establish an environment where trust is evident and the importance of creating safe spaces for after-event root cause analysis discussions.
Miller K, Ratwani R, Hose B-Z, et al. Rockville, MD: Agency for Healthcare Research and Quality; August 2024. AHRQ Publication No. 24-0010-3-EF
Electronic health records are engrained in healthcare delivery systems to support data sharing and clinical decision-making. This issue brief explores the importance of documentation, legislation supporting its quality, and reasons its improvement contributes to the value and safety of care. This publication is part of a series on diagnostic safety.
Milne-Tyte A. Health Shots. National Public Radio. July 30, 2024;
Missed or delayed diagnosis in older people is a problem fed by clinical and social complexities. This story discusses the need for geriatricians, geriatric emergency rooms, or special training for physicians in caring for older patients. A team-based approach is valued to improve diagnosis for elderly patients, address age bias, and enhance care processes for this substantial patient population.

This Month’s WebM&Ms

WebM&M Cases
Commentary by Brittany Newton, PharmD and Roslyn Seitz, MPH, MSN |
An adolescent with type 1 diabetes presented to the emergency department (ED) with dizziness, fatigue, and a “high” reading on her home blood glucose monitor. She was diagnosed with diabetic ketoacidosis (DKA) likely due to insulin pump malfunction. Despite initial treatment, her condition did not improve as expected. Later, it was discovered that an incorrect weight was used to calculate her insulin drip rate, based on a guessed weight provided by the patient upon admission. Once her actual weight was used to adjust treatment, her DKA resolved rapidly within 12 hours. The commentary discusses how human factors engineering and electronic health record (EHR) functionalities can optimize weight measurement during patient encounters and the role of clinical pharmacists in the ED to improve medication safety.
WebM&M Cases
Commentary by Robert M. Szabo, MD, MPH, FAOA |
A woman underwent surgery for carpal tunnel syndrome without complications and was discharged with instructions to avoid soaking her hand in water (to reduce infection risk) and return for suture removal in 10 days. Despite reporting symptoms such as warmth, redness, and pain in her wrist shortly after surgery, her concerns were not adequately addressed by the surgeon's office. The patient returned for suture removal and visit notes stated that the wound was not infected or swollen. However, the patient continued to report pain, swelling, redness and oozing at the incision site after suture removal. Two weeks later, she presented to the emergency department (ED) and diagnosed with a severe infection, leading to multiple hospitalizations and permanent impairment of her right hand. The commentary discusses the importance of preoperative discussions about post-operative care, including sterile practices, and the use of protocol-based management strategies for medical office personnel to ensure that patient interactions and communication are appropriately documented and acted upon
WebM&M Cases
Spotlight Case
Scott Zakaluzny, MD, FACS |
A 67-year-old man with severe low back pain was admitted to the hospital for anterior lumbar interbody fusion (ALIF) with bone autograft from the iliac crest. The surgical team had difficulty controlling bleeding and the patient left the operating room (OR) with the bone graft donor site open and oozing blood. In the postanesthesia care unit (PACU), the nurse called the attending physician three times to report hypotension and ongoing bleeding. Each time, the surgeon ordered hetastarch for volume expansion. Over the next 14 hours, the patient’s blood pressure remained at or below 90/60 with continued complaints of back and pelvic pain. The next morning, the patient was unresponsive and in severe hypovolemic shock. Electrocardiography confirmed a non-ST segment elevation myocardial infarction (NSTEMI). The patient was transferred to an intensive care unit and resuscitative efforts were initiated, but the patient expired from multiorgan failure resulting from hypovolemic shock. The commentary discusses appropriate management of ongoing intraoperative and postoperative bleeding and how a culture of safety can enable care team members to voice concerns about patient safety. 

This Month’s Perspectives

Dr. Chalapathy Venkatesan and Kathy Helak headshot image
Perspectives on Safety
Chalapathy Venkatesan, MD, MS, CPPS, Kathy Helak, MSN, BSN, RN, FACHE, CPPS, Zoe Sousane, BS, Cindy Manaoat Van, MHSA, CPPS |
Dr. Chalapathy Venkatesan is the Chief Quality and Safety Officer, and Kathy Helak is the Assistant Vice President for Patient Safety at Inova Health System. We spoke to them about Safety-II principles and their application at Inova.
Perspective
Chalapathy Venkatesan, MD, MS, CPPS, Kathy Helak, MSN, BSN, RN, FACHE, CPPS, Zoe Sousane, BS, Cindy Manaoat Van, MHSA, CPPS |
This piece provides an overview of Safety-II principles and discusses ways healthcare systems are integrating Safety-II principles into safety programs and care delivery.
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