Uncertainty in complex care situations is a common experience for both trainees and experienced practitioners. This review explores the concept of comfort with uncertainty in medicine and suggests that individual awareness of uncertainty is required to respond to the condition as it occurs. The authors advocate for educational and research strategies to further manage uncertainty in health care.

This commentary highlights the need to evaluate diagnostic reasoning in emergency medicine to address gaps and motivate research exploring factors that impair assessment.

This study found that clinical experience was the most important factor in retaining diagnostic flexibility and avoiding premature closure with an incorrect diagnosis.

This article reviews evidence on the cognitive origins of diagnostic errors and examines theories regarding both clinical reasoning and dual-process thinking.

The investigators conducted a root cause analysis of diagnostic imaging delays and found that current practices were responsible for two of the three root causes identified.