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The PSNet Collection: All Content

The AHRQ PSNet Collection comprises an extensive selection of resources relevant to the patient safety community. These resources come in a variety of formats, including literature, research, tools, and Web sites. Resources are identified using the National Library of Medicine’s Medline database, various news and content aggregators, and the expertise of the AHRQ PSNet editorial and technical teams.

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Displaying 1 - 20 of 207 Results
Gilson AM, Chladek JS, Stone JA, et al. J Patient Saf. 2024;21(1):38-47.
Unintentional misuse (e.g., drug-drug, drug-age interactions) of over-the-counter (OTC) medications can result in significant patient harm, particularly for high-risk populations, such as older adults. In this study, community pharmacies participating in the intervention redesigned pharmacy aisles to support older adults' selection of safe OTC medications (Senior Safe); control pharmacies did not make any design changes. Consumers age 65 or older at participating pharmacies were asked to read a hypothetical health scenario, select an OTC from inside the pharmacy, and then describe how they would use it. Drug-drug and drug-age misuse types were more common at control pharmacies for high-risk medications.
Kuitunen S, Saksa M, Holmström A-R. Drugs Real World Outcomes. 2024;Epub Dec 11.
Understanding how and when medication errors occur is necessary to implement medication management safety strategies. This study determined that most self-reported high-alert medication errors in a children’s hospital were associated with administration and prescribing. One-quarter of incidents included two to four errors, and wrong dose or omission were the most common. Systemic defenses are required to reduce wrong dose, omission, and documentation errors.
ISMP Medication Safety Alert! Acute Care. October 31, 2024;29(22 & 23):1-5;1-4.
Tubing misconnections are known to cause patient safety incidents. This two-part series examines characteristics of misconnections, how often they occur, and what can be done about them. The series shares the results of a national survey documenting the problem and strategies to ward off tubing misconnections. Strategies include training patients and clinicians, using simulation to analyze processes for potential failures, and completing an FMEA prior to any equipment conversion program.
Special or Theme Issue
Harbell MW, ed. Curr Opin Anaesthesiol. 2024;37(6):666-742.
Despite consummate efforts to improve safety, errors still occur in anesthesiology. This special collection covers a range of topics affecting safe care in the specialty, including pain management, incident reporting, psychological safety, and human factors.
Institute for Safe Medication Practices; October 2024.
Like other medication processes, vaccine administration is vulnerable to errors. This report examined 1,987 reports submitted to the ISMP vaccine errors reporting initiative over a 2-year period. The data highlight various clinical settings where the errors occurred, the types of errors, and show that a majority of the submitted errors reached the patient.
Thurgood Giarman A, Hays HL, Badeti J, et al. Inj Epidemiol. 2024;11(1):51.
Errors in the administration of diabetes medications can result in emergency department visits, hospitalizations, and patient harm. Using National Poison Data System data, researchers found that errors involving diabetes medications administered outside of healthcare facilities increased by nearly 280% from 2000 to 2011 and by 15% from 2011 to 2021. About 10% of those errors involved a serious outcome (e.g., hospital admission or death). Insulin-related errors were most common, but metformin accounted for 59% of deaths.
WebM&M Case Commentary by Brittany Newton, PharmD and Roslyn Seitz, MPH, MSN| August 28, 2024

An adolescent with type 1 diabetes presented to the emergency department (ED) with dizziness, fatigue, and a “high” reading on her home blood glucose monitor. She was diagnosed with diabetic ketoacidosis (DKA) likely due to insulin pump malfunction. Despite initial treatment, her condition did not improve as expected. Later, it was discovered that an incorrect weight was used to calculate her insulin drip rate, based on a guessed weight provided by the patient upon admission. Once her actual weight was used to adjust treatment, her DKA resolved rapidly within 12 hours.

Nguyen PTL, Phan TAT, Vo VBN, et al. Int J Clin Pharm. 2024;46(5):1024-1033.
The fast-paced and complex environment of the emergency department (ED) can threaten patient safety. In this meta-analysis, the pooled prevalence of medication errors in the ED was 22%. The researchers estimated that 36% of patients experienced a medication error in the ED, with about 43% of these errors being potentially harmful but without leading to death.
Stolte AR, Siwy YM, Tanios SB, et al. Patient Safety. 2024;6(1):117504.
System-based strategies are considered the most effective in reducing adverse events. This study evaluates the proposed action plan of an academic medical center following a fatal medication administration event against the Institute of Safe Medication Practices’ (ISMP) hierarchy of effectiveness. Only two of the 25 strategies were considered highly effective, high leverage system-based strategies. The authors also recommend fostering a “just culture” that advocates for system accountability.
WebM&M Case Paul MacDowell, PharmD, BCPS and Eloh McGee, PharmD| July 31, 2024

A 19-month-old boy was being transferred to a tertiary medical center from another emergency department after undergoing comprehensive resuscitation efforts due to cardiopulmonary arrest. The transport clinician intended to administer rocuronium (a neuromuscular blocking agent) to treat ventilator desynchrony, but instead unintentionally administered flumazenil (a benzodiazepine antagonist). The clinician promptly corrected the error by administering the appropriate dose of rocuronium.

ISMP Medication Safety Alert! Acute Care. 2024;29(8):1-4.

A multitude of latent and active failures typically contribute to harmful medication errors in hospitals. This article examines a prolonged intravenous medication administration error and describes “holes in the Swiss cheese” that enabled the failure. Recommendations for improvement discussed in this article include daily review of medications, look-alike medication management, and infusion line verification.

Ruskin KJ, ed. Int Anesthesiol Clin. 2024;62(2):1-65.

Anesthesia is a vital component of surgical care that can be compromised due to human and equipment factors. This special issue highlights a range of topics exploring Safety II, safety culture implementation, and artificial intelligence applications as they affect safe anesthesia provision in the operating room.
Curated Libraries
March 21, 2024
Organizational learning is an environmental state that ensures lessons from lived experience within a work environment are coupled with data then fed into, and embedded within, the organization’s policies and culture to ensure continuous improvement and support collective high reliability. This curated library focuses on concepts and activities...
Whitaker DK, Lomas JP. Anaesthesia. 2024;79(2):119-122.
Simplifying complex processes is a strategy to engineer safety into health care. This article discusses the use of prefilled syringes as a tactic to reduce the potential for error in intravenous medication administration. The author argues for broader acceptance of this strategy across the practice of anesthesiology.
Konwinski L, Steenland C, Miller K, et al. J Patient Saf. 2024;20(3):209-215.
Independent double checking (IDC) has long been recommended to increase medication administration safety, but research on its effectiveness has been mixed. In this study, mandatory IDC were discontinued in a pediatric intensive care unit (except for total parental nutrition and chemotherapy which followed a different administration process). Administration error rates and patient harm were not different in the double checking and single checking periods, and nurse attitudes towards single checking improved during the single checking period.
Booth JP, Hartman AD. Hosp Pharm. 2024;59(1):47-55.
Intensive strategies are required to prevent high-risk medication errors from reaching the patient. This article describes the development of a framework to identify common causes of medication errors and human factors-related strategies to prevent harm such as manufacturer or organizational premixed/prefilled products and separate storage.
WebM&M Case Kimberly Beres, DNAP, MHS, CRNA and Maria Cristina Gutierrez, MD | January 31, 2024

A patient presented for open reduction and internal fixation of a fractured radius under an ultrasound-guided supraclavicular brachial plexus nerve block. The initial attempt at local anesthesia using 2% lidocaine was inadequate, necessitating a subsequent lidocaine injection, followed by the procedural block using 20 ml of 0.375% plain bupivacaine. The patient developed progressive dyspnea and diminishing oxygen saturation, prompting emergent intubation and initiation of mechanical ventilation.

Special or Theme Issue

Arnal-Velasco, D, ed. Curr Opin Anaesthesiol. 2023;36(6):649-705.

Adoption of new ideas is necessary to create safety in the perioperative environment. This collection of reviews illustrates relationships and tensions between technology, human factors and safety management that create the sociotechnical system within which technology is used to deliver anesthesia. Topics covered include artificial intelligence, decision making and perioperative deterioration.
Lim PJH, Chen L, Siow S, et al. Int J Qual Health Care. 2023;35(4):mzad086.
Surgical safety checklists (SCC) are utilized around the world, but checklist completion at the operating room level remains inconsistent. This review summarizes facilitators and barriers to completion. Resistance or endorsement at the individual surgeon level remains a significant factor in SSC completion. Early inclusion of frontline staff in evaluation and implementation supported increased use.
WebM&M Case Nidhi Patel Jain, PharmD, MBAc and David Dakwa, PharmD, MBA, BCPS, BCSCP | October 31, 2023

A 2-year-old girl presented to the emergency department (ED) with joint swelling and rash following an upper respiratory infection. After receiving treatment and being discharged with a diagnosis of allergic urticaria, she returned the following day with worsening symptoms. Suspecting an allergic reaction to amoxicillin, the ED team prepared to administer methylprednisolone. However, the ED intake technician erroneously switched the patient’s height and weight in the electronic health record (EHR), resulting in an excessive dose being ordered and dispensed.