The fifth annual edition of the AHRQ Hospital Survey on Patient Safety Culture comparative database presents benchmarking data for safety culture from more than 1000 hospitals nationwide, including trending data on changes in safety culture perception over time for more than 500 hospitals. The full report contains detailed comparative data for various hospital characteristics (type and size) and respondent characteristics (work areas, staff positions, and direct patient contact). Overall perception of safety culture improved compared with prior reports, and respondents specifically noted improvements in teamwork and management support of safety. However, persistent concerns were voiced about the safety of handoffs, and most respondents did not voluntarily report safety incidents.