Impact of a national multimodal intervention to prevent catheter-related bloodstream infection in the ICU: the Spanish experience.
Approach to Improving Safety
Setting of Care
A multifaceted intervention that included checklists and efforts to improve safety culture resulted in a marked reduction in central line–associated bloodstream infections in a large cohort of intensive care units in Spain. The intervention was modeled on the landmark Keystone ICU study, and its success illustrates the generalizability of this approach to different countries and health care systems.