Health care–associated infections among critically ill children in the US, 2007–2012.
Approach to Improving Safety
Setting of Care
This large cohort study of 174 hospitals examined rates of central line–associated bloodstream infections (CLABSIs), ventilator-associated pneumonias, and catheter-associated urinary tract infections in neonatal and pediatric intensive care units (ICUs) across the United States. Between 2007 and 2012, there were remarkable reductions in these hospital-acquired infections among critically ill infants and children. In pediatric ICUs, CLABSIs plummeted from about 4.7 to 1.0 per 1000 central-line days, while ventilator-associated pneumonias dropped from 1.9 to 0.7 per 1000 ventilator-days. The trends were similar in neonatal ICUs. The authors estimate that the decrease in CLABSI rates alone not only enhanced patient safety but also saved $131 million for these hospitals during the study period. A recent AHRQ WebM&M perspective focused on hospital infection prevention programs.