Study
Published May 2016

Ambulatory computerized prescribing and preventable adverse drug events.

Overhage JM, Gandhi TK, Hope C, et al. J Patient Saf. 2016;12:69-74.

Topics
Resource Type
- Journal Article
  - › Study
Approach to Improving Safety
- Computerized Provider Order Entry (CPOE)
Safety Target
- Medication Errors/Preventable Adverse Drug Events
Setting of Care
- Ambulatory Care
Clinical Area
- Primary Care
Target Audience
Error Types
- Epidemiology of Errors and Adverse Events
Origin/Sponsor
- United States of America

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Overhage JM ; Gandhi TK ; Hope C; et al. Ambulatory computerized prescribing and preventable adverse drug events. J Patient Saf. 2016; 12: 69-74

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Adverse drug events (ADEs) are a common source of patient harm in the ambulatory setting. A substantial proportion of ADEs are caused by preventable errors in medication prescribing or monitoring. The introduction of computerized provider order entry (CPOE) has been shown to reduce the rate of medical errors in the inpatient setting. This before–after study examined rates of ADEs in primary care practices that implemented a CPOE system in Boston and Indianapolis. At baseline, the potential ADE rate was more than seven-fold greater in Indianapolis compared to Boston. Following CPOE implementation, this rate decreased by 56% in Indianapolis but increased by 104% in Boston, and there was no change overall in preventable ADEs. A recent PSNet annual perspective reviewed the relationship and current evidence linking CPOE and patient safety.

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