• Review
  • Published December 2017

Symptom–Disease Pair Analysis of Diagnostic Error (SPADE): a conceptual framework and methodological approach for unearthing misdiagnosis-related harms using big data.

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Patient safety measurement remains challenging. This article describes a framework to address gaps in measuring diagnostic error. The authors propose utilizing big data to develop diagnostic performance dashboards and benchmarking tools that support proactive learning and improvement strategies.

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