• Commentary
  • Published November 2018

Preventing central line–associated bloodstream infections in the intensive care unit: application of high-reliability principles.

Although central line–associated bloodstream infections (CLASBI) have been a target of safety improvement efforts, they continue to occur in health care. This project report outlines a bundled approach to reducing CLASBIs in an intensive care unit that focused on team collaboration, communication, and evaluation. These elements were built on high reliability principles to establish a culture that contributed to the program's sustained improvements.

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