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Yu DT, Seger DL, Lasser KE, et al. Pharmacoepidemiol Drug Saf. 2011;20:192-202.
Preventing overuse of potentially dangerous medications has continued to be a challenge for the safety movement, despite increasing use of technological solutions such as computerized order entry and clinical decision support. This study targeted prescribing for drugs classified as requiring a black box warning by implementing reminders within an ambulatory electronic medical record. Certain specific alerts, such as warning against prescribing drugs contraindicated in pregnancy or those with high potential for drug–drug interactions, were effective. However, overall prescribing of contraindicated medications did not decrease. Prior studies have also found limited benefit from prescribing reminders in ambulatory care, and a recent systematic review found that point-of-care clinician reminders, such as those used in this study, generally achieved only limited successes.
Brownlee S, Garber J. Brookline, MA: Lown Institute; 2019.
Overprescribing is a common problem that contributes to patient harm. This report examines financial, clinical, and societal trends of medication overuse and inappropriate polypharmacy in older Americans. A culture of prescribing, deficits in information and knowledge, and fragmented care contribute to the problem. The report provides interventions to improve the safety of prescribing, including developing deprescribing guidelines, raising awareness among providers and patients about medication overload, and implementing team-based care models.