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Journal Article > Review
The effect of computerized physician order entry on medication prescription errors and clinical outcome in pediatric and intensive care: a systematic review.
van Rosse F, Maat B, Rademaker CMA, van Vught AJ, Egberts ACG, Bollen CW. Pediatrics. 2009;123:1184-1190.
Computerized provider order entry (CPOE) continues to be hailed as a solution to preventing medication errors. While past research demonstrates its benefits in reducing serious medication errors, debate exists about its clinical benefits and unintended consequences. This systematic review builds on the existing literature by examining the impact of CPOE in pediatric and intensive care settings. Investigators analyzed data from twelve studies and discovered that medication prescription errors are in fact reduced after CPOE adoption. However, evidence of clinical benefit remains lacking, and the authors conclude that the quality of the implementation process is the key factor in success.
Journal Article > Study
Time-dependent drug–drug interaction alerts in care provider order entry: software may inhibit medication error reductions.
van der Sijs H, Lammers L, van den Tweel A, et al. J Am Med Inform Assoc. 2009;16:864-868.
Alerts within a computerized provider order entry system were not able to prevent medication errors resulting from drug–drug interactions. The authors hypothesize that the inadequacy of the alerts themselves was responsible for this failure, with problems including an excessive number of false-positive alerts and unclear instructions for preventing drug interactions.