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Lydia C. Siegel, MD; Tejal K. Gandhi, MD, MPH; January 2009
Four months after surgery, a woman with osteosarcoma receiving outpatient chemotherapy was admitted for possible cellulitis. Discharged home on methotrexate and antibiotics, the patient developed methotrexate toxicity, partly due to a drug interaction.
World Alliance for Patient Safety. Geneva, Switzerland: World Health Organization; 2008.
Through a discussion of a vincristine administration error, this booklet and video illustrate how system weaknesses can contribute to failure.
Journal Article > Study
Alkan A, Yasar A, Karci E, et al. Support Care Cancer. 2017;25:229-236.
Specific medication classes have been deemed potentially inappropriate for older adults due to high risk of adverse drug events. This medical record review study uncovered significant rates of drug–drug interactions and use of potentially inappropriate medications in cancer patients older than 65, consistent with prior studies. The authors suggest that strategies to improve prescribing in older adults are needed.