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Journal Article > Study
From physician intent to the pharmacy label: prevalence and description of discrepancies from a cross-sectional evaluation of electronic prescriptions.
Cochran GL, Klepser DG, Morien M, Lomelin D, Schainost R, Lander L. BMJ Qual Saf. 2014;23:223-230.
One major safety advantage of computerized provider order entry (CPOE) systems lies in their ability to prevent adverse drug events due to prescribing errors. In the outpatient setting, use of electronic prescriptions is growing thanks to studies demonstrating that e-prescribing reduces medication errors. However, as with CPOE in general, increasing use of e-prescribing is leading to greater recognition of new types of errors associated with this new technology. This study analyzed the frequency of unintended discrepancies in e-prescriptions from three primary care clinics by comparing the prescription information in the prescribing physician's note with the order entered into the e-prescribing system and the medication ultimately dispensed by the pharmacy. The investigators found that errors occurred at each stage of the process, with a small but significant rate of discrepancies between both physician notes and e-prescriptions and between e-prescriptions and the medication dispensed. These errors often occurred when providers entered free-text instructions into the e-prescribing system, as found in prior research. The potential safety benefits and hazards of e-prescribing are discussed in detail in an AHRQ WebM&M commentary.
Journal Article > Study
Abramson EL, Bates DW, Jenter C, et al. J Am Med Inform Assoc. 2012;19:644-648.
This study, one of the first to analyze prescribing errors in community primary care practices, found a remarkably high rate of errors. Nearly one in four prescriptions contained at least one error in dosing, frequency, or patient instructions, and a startling proportion of prescriptions had illegibility errors as well. Computerized provider order entry (CPOE) could have prevented a large proportion of these errors, and recent studies have shown that CPOE can decrease prescribing errors in community-based office practices. A Patient Safety Primer discusses outpatient medication prescribing errors and other pressing safety issues in outpatient practice.