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Journal Article > Study
Alpert A, Jacobson M. Clin Pharmacol Ther. 2019 Feb 10; [Epub ahead of print].
Drug shortages have become more frequent and may lead to delays in treatment or failure to deliver the appropriate drug, an error of omission. This secondary data analysis examined how oncology drug shortages affected use of chemotherapy medications among patients with newly diagnosed cancer as measured by Medicare claims data. The changes in utilization varied by medication; overall, drug shortages had only a modest impact on the delivery of these drugs to patients with newly diagnosed cancer. This finding contrasts with a prior study showing patient harm related to drug shortages, and the authors recommend further study to understand how to identify and mitigate clinically relevant drug shortages. A WebM&M commentary discussed strategies for preventing or minimizing adverse events associated with drug shortages.
Talsma J. Drug Topics. June 15, 2013.
Discussing the current state of and efforts to address drug shortages, this news article notes a reduction in chemotherapy delays and reveals persistent barriers to improvement.
Journal Article > Review
Rider AE, Templet DJ, Daley MJ, Shuman C, Smith LV. J Pharm Pract. 2013;26:183-191.
Drug shortages have been shown to have serious clinical consequences for affected patients. This review article outlines a systematic approach for managing drug shortages.
Sun LH. Washington Post. April 10, 2012.
This newspaper article discusses strategies hospitals are using to address drug shortages.
Silver Spring, MD: US Food and Drug Administration; October 31, 2011.
This report outlines the complex nature of drug shortages and suggests strategies to augment the FDA's efforts to address them.