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Approach to Improving Safety
- Communication Improvement 49
- Culture of Safety 5
- Education and Training 19
- Error Reporting and Analysis 56
- Human Factors Engineering 57
- Legal and Policy Approaches 4
- Logistical Approaches 11
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Quality Improvement Strategies
48
- Reminders 10
- Specialization of Care 18
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- Technologic Approaches 374
Safety Target
- Alert fatigue 24
- Device-related Complications 9
- Diagnostic Errors 4
- Discontinuities, Gaps, and Hand-Off Problems 24
- Identification Errors 8
- Interruptions and distractions 4
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Medical Complications
11
- Delirium 1
- Medication Safety
- Surgical Complications 5
- Transfusion Complications 2
Clinical Area
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Medicine
261
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Internal Medicine
118
- Geriatrics 19
- Pediatrics 55
- Primary Care 26
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Internal Medicine
118
- Nursing 26
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Target Audience
- Health Care Executives and Administrators 325
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Health Care Providers
265
- Nurses 36
- Pharmacists 62
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Non-Health Care Professionals
- Engineers 15
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Asia
12
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- Europe 69
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North America
294
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Search results for "Information Professionals"
- Information Professionals
- Medication Errors/Preventable Adverse Drug Events
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Journal Article > Review
Interventions to reduce nurses' medication administration errors in inpatient settings: a systematic review and meta-analysis.
Berdot S, Roudot M, Schramm C, Katsahian S, Durieux P, Sabatier B. Int J Nurs Stud. 2016;53:342-350.
This meta-analysis examined the efficacy of interventions to improve the safety of medication administration. Researchers looked at studies that used training methods (e.g., simulation) and technology approaches (e.g., computerized physician order entry and automated medication dispensing systems). The authors conclude that more randomized or experimental trials are needed in order to characterize the effect of these interventions, although they acknowledge the increasing implementation of barcode medication administration as a safety strategy.
Journal Article > Review
A safe practice standard for barcode technology.
Leung AA, Denham CR, Gandhi TK, et al. J Patient Saf. 2015;11:89-99.
Barcode technology has been advocated as a strategy to reduce medication errors. This narrative review explored barcoding solutions applied in various care settings and found that they resulted in notable reductions of transcription, dispensing, and administration errors. The authors recommend standards for successful implementation of barcode technology systems.
Journal Article > Study
Assessing the potential adoption and usefulness of concurrent, action-oriented, electronic adverse drug event triggers designed for the outpatient setting.
Mull HJ, Rosen AK, Shimada SL, et al. EGEMS (Wash DC). 2015;3:1116.
Trigger tools have been shown to be an efficient way to screen for adverse events. This AHRQ-funded study assessed the usefulness of different adverse drug event triggers in the outpatient setting. Five of the triggers performed reasonably well for either detecting harm or leading to a change in care plan.
Journal Article > Study
Best practices: an electronic drug alert program to improve safety in an accountable care environment.
Griesbach S, Lustig A, Malsin L, Carley B, Westrich KD, Dubois RW. J Manag Care Spec Pharm. 2015;21:330-336.
This study of a quality improvement initiative found that automated screening of prescribing data uncovered many potential adverse drug events. Prescribers were notified about these safety concerns, and almost 80% of these potential adverse drug events were resolved through prescription changes. The extent of patient harm which occurred or was averted was not reported. This work suggests that real-time data from electronic prescribing could be harnessed to improve patient safety, as others have suggested.
Journal Article > Study
Role of computerized physician order entry usability in the reduction of prescribing errors.
Peikari HR, Zakaria MS, Yasin NM, Shah MH, Elhissi A. Healthc Inform Res. 2013;19:93-101.
Computerized provider order entry users felt that the usability of the system was the most important factor in its ability to prevent medication prescribing errors.
Perspectives on Safety > Interview
In Conversation With…David C. Classen, MD, MS
Trigger Tools, May 2012
One of the pioneers of the trigger tool methodology for detecting adverse events, Dr. Classen is Chief Medical information Officer at Pascal Metrics and Associate Professor of Medicine at the University of Utah.
Journal Article > Review
A systematic review of the psychological literature on interruption and its patient safety implications.
- Classic
Li SY, Magrabi F, Coiera E. J Am Med Inform Assoc. 2012;19:6-12.
Interruptions pose a significant safety hazard for health care providers performing complex tasks, such as signout or medication administration. However, as prior research has pointed out, many interruptions are necessary for clinical care, making it difficult for safety professionals to develop approaches to limiting the harmful effects of interruptions. Reviewing the literature on interruptions from the psychology and informatics fields, this study identifies several key variables that influence the relationship between interruption of a task and patient harm. The authors provide several recommendations, based on human factors engineering principles, to mitigate the effect of interruptions on patient care. A case of an interruption leading to a medication error is discussed in this AHRQ WebM&M commentary.
Journal Article > Study
Using FDA reports to inform a classification for health information technology safety problems.
Magrabi F, Ong MS, Runciman W, Coiera E. J Am Med Inform Assoc. 2012;19:45-53.
This study reviewed nearly 900,000 reports from the FDA Manufacturer and User Facility Device Experience database (MAUDE) and identified 678 reports describing health information technology issues. Investigators uncovered problems with software functionality, system configuration, interface with devices, and network configuration as new categories to the existing classification system.
Journal Article > Review
The effectiveness of integrated health information technologies across the phases of medication management: a systematic review of randomized controlled trials.
McKibbon KA, Lokker C, Handler SM, et al. J Am Med Inform Assoc. 2012;19:22-30.
This systematic review identified 87 randomized controlled trials assessing the effect of information technology on various aspects of medication safety, including studies of computerized provider order entry. Although processes of care consistently improved, few studies demonstrated improvement in clinical outcomes.
Journal Article > Study
Errors and electronic prescribing: a controlled laboratory study to examine task complexity and interruption effects.
Magrabi F, Li SY, Day RO, Coiera E. J Am Med Inform Assoc. 2010;17:575-583.
Interruptions during the medication administration process have been linked to an increased risk of error. This simulation study investigated the effect of interruptions on medication prescribing errors, using a controlled experimental design during which physicians were interrupted while prescribing within a computerized provider order entry system. Interruptions did not result in an increase in prescribing errors, but did significantly increase the time needed to complete complex prescribing tasks. The investigators hypothesize that CPOE systems provide visual cues that may help providers resume interrupted tasks without increasing the potential for error.
Journal Article > Commentary
Medical research and the Institutional Review Board: the librarian's role in human subject testing.
Robinson JG, Gehle JL. Ref Serv Rev. 2005;33:20-24.
The authors discuss their organization's response to a 2001 incident in which an incomplete bibliographic review played a role in the death of a research volunteer. They outline an initiative to involve librarians in evidentiary review for clinical trials to ensure the safety of research subjects.
Journal Article > Study
Incidence of clinically relevant medication errors in the era of electronically prepopulated medication reconciliation forms: a retrospective chart review.
Stockton KR, Wickham ME, Lai S, et al. CMAJ Open. 2017;5:E345-E353.
An accurate list of patient medications is a necessary precursor for safe medication use. One strategy to improve medication reconciliation is to provide a list of dispensed outpatient medications to inpatient clinicians upon hospital admission via an electronic medication reconciliation process. This retrospective chart review study compared a research pharmacist–generated gold standard medication list to the actual medications ordered during an admission after such a process was implemented. The study team identified medication discrepancies between the pharmacist-generated and admission-ordered medication lists and noted any inappropriately prescribed or continued medications. Medication errors were present in nearly half of the patient records; about 9% of errors were clinically important. The authors raise concerns that electronically prepopulated medication reconciliation forms may actually adversely impact medication safety. A previous WebM&M commentary discussed how to enhance accuracy of medication reconciliation.
Journal Article > Study
Prescription errors related to the use of computerized provider order-entry system for pediatric patients.
Alhanout K, Bun SS, Retornaz K, Chiche L, Colombini N. Int J Med Inform. 2017;103:15-19.
Computerized provider order entry has been shown to decrease adverse drug events, but it can also introduce new medication errors. This retrospective study examined medication ordering errors intercepted by pharmacists for pediatric patients. As with prior studies in pediatrics, this investigation uncovered dosing errors associated with weight-based dosing, including calculation errors and missing weight information. The most common medication associated with errors was acetaminophen, which can cause severe harm if incorrectly dosed. The authors call for improving electronic health record prescribing interfaces, better user training, and enhancing communication among providers to prevent medication errors.
Journal Article > Study
Analysis of variations in the display of drug names in computerized prescriber-order-entry systems.
Quist AJL, Hickman TT, Amato MG, et al. Am J Health Syst Pharm. 2017;74:499-509.
Evidence suggests that computerized provider order entry (CPOE) systems improve medication safety by mitigating prescribing errors. However, CPOE systems may contribute to errors when user-centered design is not taken into account. In this study, researchers standardized the assessment of 10 distinct inpatient and ambulatory CPOE systems across 6 health care institutions to determine how variation in drug name display may increase the risk of medication errors. Using test patient scenarios, they found significant variation in drug name display, including inconsistencies with regard to the display of brand and generic names. Providers could theoretically prescribe both the brand and generic drug, increasing the risk for patient harm. A recent Annual Perspective discussed the benefits and limitations of CPOE with regard to patient safety.
Newspaper/Magazine Article
Medication errors attributed to health information technology.
Lawes S, Grissinger M. PA-PSRS Patient Saf Advis. March 2017;14:1-8.
The unintended consequences associated with health information technologies for medication management are well documented. Drawing from 889 medication error reports submitted over a 6-month period, this analysis found that more than half of the recorded incidents were associated with computerized provider order entry. Staff reporting of medication errors and near misses is key to identifying trends and consequently developing system improvements to reduce risks of such incidents.
Journal Article > Study
Meaningful use of health information technology and declines in in-hospital adverse drug events.
- Classic
Furukawa MF, Spector WD, Limcangco MR, Encinosa WE. J Am Med Inform Assoc. 2017 Feb 16; [Epub ahead of print].
Electronic health records have both safety benefits and unintended consequences. This analysis used data from the 2010–2013 Medicare Patient Safety Monitoring System to compare the incidence of in-hospital adverse events among hospitals that did and did not meet meaningful use requirements for health information technology (IT), according to the Healthcare Information Management Systems Society Analytics Database. Investigators found that hospitals that met meaningful use criteria also reported fewer adverse events. Although the study design does not establish a causal relationship between implementation of health IT and the decline in adverse events, the authors argue that these advances in health IT contributed to this patient safety improvement.
Journal Article > Commentary
Responsible e-prescribing needs e-discontinuation.
Fischer S, Rose A. JAMA. 2017;317:469-470.
E-prescribing is a key strategy to improve medication safety by addressing illegible prescriptions, order omissions, and dosage confusion. However, there have been unintended consequences such as the inability to discontinue medications ordered electronically. This commentary reviews problems associated with this unintended consequence and suggests that enabling electronic cancellation of prescriptions can help address the issue. A WebM&M commentary discussed a case involving an electronic prescribing error.
Journal Article > Study
Screening for medication errors using an outlier detection system.
Schiff GD, Volk LA, Volodarskaya M, et al. J Am Med Inform Assoc. 2017;24:281-287.
Medication errors continue to occur despite implementation of computerized provider order entry and clinical decision support systems. This study sought to assess whether medication error alerts might have a greater impact on mitigating such errors if they were generated based on outlier detection screening. Researchers analyzed data from the electronic health records of 747,985 outpatients to identify outliers that might indicate a medication error. They then chose 300 charts from the 15,693 resulting alerts. The charts were reviewed using a coding system to evaluate the utility of the alerts generated. About 75% of the chart-reviewed alerts created by the screening system identified possible medication errors. The authors suggest that using this type of outlier detection screening to generate alerts might improve existing clinical decision support systems' ability to mitigate medication errors. A prior WebM&M commentary discussed an incident involving an electronic prescribing error.
Journal Article > Study
EHR-related medication errors in two ICUs.
Carayon P, Du S, Brown R, Cartmill R, Johnson M, Wetterneck TB. J Healthc Risk Manag. 2017;36:6-15.
Despite the demonstrated success of technology in reducing medication errors, preventable adverse drug events remain a significant source of harm to patients. Researchers analyzed data on medication safety events in 2 ICUs at a medical center and found 1622 preventable adverse drug events among 624 patients. About one third of these events were related to electronic health record use, including duplicate orders.
Journal Article > Commentary
Medication safety in the neonatal intensive care unit: big measures for our smallest patients.
Rostas SE. J Perinat Neonatal Nurs. 2017;31:15-19.
Medication errors are common in the neonatal intensive care unit. This commentary outlines various strategies one teaching hospital has utilized to reduce risks of medication errors in this care setting, such as use of computerized provider order entry and smart pumps.
