Journal Article

Diagnostic error as a result of drug–laboratory test interactions.

van Balveren JA; Verboeket-van de Venne WPHG; Erdem-Eraslan L; de Graaf AJ; Loot AE; Musson REA; Oosterhuis WP; Schuijt MP; van der Sijs H; Verheul RJ; de Wolf HK; Kusters R; Hoedemakers RMJ; Dutch Society for Clinical Chemistry and Laboratory Medicine; task group "SMILE": Signalling Medication Interactions and Laboratory test Expert system.

Failure to recognize potential drug–laboratory test interactions can lead to misinterpretation of results, misdiagnosis, and unneeded tests or therapies. This review examines the evidence on this issue and suggests that decision support technologies can help avoid these errors.