Ensuring patients have an understanding of their diagnoses and care plan is a critical component of patient engagement and can improve safety. Using semi-structured phone interviews and electronic health record (EHR) review, this study examined patient understanding about their inpatient care and discharge plan. Although the majority of patients (>90%) felt confident in their knowledge of their diagnosis and treatment plan, chart review indicated that only 43% to 64% correctly recalled details about their diagnosis, treatment, post-discharge treatment plan, and medication changes.