Clinical outcomes associated with medication regimen complexity in older people: a systematic review.
Wimmer BC, Cross AJ, Jokanovic N, et al. Clinical Outcomes Associated with Medication Regimen Complexity in Older People: A Systematic Review. J Am Geriatr Soc. 2016;65(4):747-753. doi:10.1111/jgs.14682.
Older adults are at increased risk for adverse drug events, especially those who take high-risk medications. This systematic review found moderate evidence to suggest that medication regimen complexity in older adults is associated with nonadherence and higher rates of hospitalization.