Prescription opioid exposures among children and adolescents in the United States: 2000–2015.

Opioid use remains a high priority safety issue. This retrospective study of data from the National Poison Data System reveals that opioid ingestions by children increased from 2000–2009 and then began to decline. Hydrocodone was the most common opioid implicated in these cases, and adolescents were most likely to experience severe harm.